Author

Tarek A. Samad

Lundbeck (Denmark)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Alzheimer’s Disease Neuroimaging Initiative· 1 shared Carlos E. Pedraza· 1 shared Carlos GuijasiD· 1 shared Carrie Garron· 1 shared Cassandra L. Henry· 1 shared Cici BaueriD· 1 shared Clayton Hutton· 1 shared David A. Kummer· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperNeuroscience

Alzheimer’s Disease Neuroimaging Initiative

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Author profile →

3 papers

Recent·Most cited

GPR17 modulates oligodendrocyte precursor cell maturation during development but has limited impact on myelin regeneration following demyelinating insults

Kristin Puorro-Radzwill, Petti T. Pang, Stefanie Giera, Guoqing Sheng, Jonathan E. Farley, Carrie Garron, Sanjay J. Danthi, Joseph Gans, Dinesh Kumar, Rajiv G. Agrawal, Dinesh S. Bangari, Susan Ryan, Nilesh Pande, Tarek A. Samad, Sabine Gratzer, Carlos E. Pedraza

This study investigates GPR17's role in oligodendrocyte precursor cell maturation and myelin regeneration, finding limited impact on myelin repair after injury.

bioRxiv · Jul 8, 2025 · PreprintNeuroscience

Base exchange inhibitors of SARM1 form mononucleotide adducts and activate SARM1 in vivo

Holly T. Reardon, Carlos Guijas, Jason R. Clapper, Julia A. Callender, Ellen M. Kozina, Francisco J. Sarabia, Clayton Hutton, Dylan M. Herbst, Taylor Andalis, Luka Perehinets, Cassandra L. Henry, Terry P. Lebold, David A. Kummer, Jacqueline L. Blankman, John J. M. Wiener, , Tarek A. Samad

The paper shows that SARM1 base exchange inhibitors form mononucleotide adducts and paradoxically activate SARM1, leading to increased cADPR and cADPR/NAD ratios in vivo.

bioRxiv · Apr 22, 2025 · PreprintNeuroscience

Free water in white matter differentiates MCI and AD from control subjects

Matthieu Dumont, Maggie Roy, Pierre‐Marc Jodoin, Félix C. Morency, Jean‐Christophe Houde, Zhiyong Xie, Cici Bauer, Tarek A. Samad, Koene R. A. Van Dijk, James A Goodman, Maxime Descoteaux, Alzheimer’s Disease Neuroimaging Initiative

The paper develops a free water (FW) processing pipeline to differentiate mild cognitive impairment (MCI) and Alzheimer's disease (AD) from controls using diffusion MRI data.

Frontiers in Aging Neuroscience · Oct 2, 2019Peer-reviewedNeuroscience