Spatial metabolic gradients in the liver and small intestine
Laith Z. Samarah, Clover Zheng, Xi Xing, Won Dong Lee, Amichay Afriat, Uthsav Chitra, Michael Robert MacArthur, Wenyun Lu, Connor S.R. Jankowski, Cong Ma, Craig J. Hunter, Michael D. Neinast, Daniel Weilandt, Benjamin J. Raphael, Joshua D. Rabinowitz
This study maps spatial metabolic gradients in murine liver and intestine using integrated experimental-computational methods, revealing distinct metabolic patterns and fructose-induced metabolic derangements.
Nature · Oct 15, 2025Peer-reviewedBiochemistry