Laith Z. Samarah

The paper uses in vivo isotope tracing and AI to identify biosynthetic origins of unknown metabolites, revealing new metabolic pathways and age-related changes.

COSIE is a computational framework that integrates multiple spatial omics modalities to generate high-resolution molecular landscapes, outperforming existing methods across diverse datasets.

This study maps spatial metabolic gradients in murine liver and intestine using integrated experimental-computational methods, revealing distinct metabolic patterns and fructose-induced metabolic derangements.