Cody A Despins

Self-multimerization of mRNA LNP-derived antigen improves antibody responses

This study compares multimerization domains in mRNA LNP vaccines, finding that IMX313 enhances antibody responses more than other domains.

Isolation-by-distance and population-size history inferences from the coho salmon (Oncorhynchus kisutch) genome

The paper uses genome-wide data to infer isolation-by-distance and population size history in coho salmon, identifying genes associated with latitude and potential osmoregulation roles.

Genome assembly, transcriptome and SNP database for chum salmon (Oncorhynchus keta)

This paper generates a reference genome and SNP database for chum salmon, identifies geographic genetic variation, and links SNPs to phenotypic sex.

Modulation of the host cell transcriptome and epigenome by Fusobacterium nucleatum

This study investigates how three Fusobacterium nucleatum strains modulate host cell transcriptomes and epigenomes through RNA-seq and ChIP-seq, revealing inflammation-related gene upregulation and chromatin remodeling during host cell invasion.

Loss of genetic variation and sex determination system in North American northern pike characterized by whole-genome resequencing

The paper uses whole-genome resequencing to analyze genetic diversity and sex determination system loss in northern pike across North America, finding reduced diversity and a patchwork distribution of the amhby gene.