Hv1 proton channel is essential for splenic antibacterial defense and immune homeostasis during the chronic phase of traumatic brain injury in male mice
Zhuofan Lei, Romeesa Khan, Yun Li, Kavitha Brunner, Cole R Sebok, Patrick J. Devlin, Junyun He, Junfang Wu
This study shows that Hv1 deficiency in mice leads to increased mortality and immune dysfunction after TBI, with significant effects on splenic antibacterial defense and immune homeostasis.
bioRxiv · Aug 5, 2026 · PreprintNeuroscience