Patrick J. Devlin

Hv1 proton channel is essential for splenic antibacterial defense and immune homeostasis during the chronic phase of traumatic brain injury in male mice

This study shows that Hv1 deficiency in mice leads to increased mortality and immune dysfunction after TBI, with significant effects on splenic antibacterial defense and immune homeostasis.

Neuropathological hallmarks during the chronic phase of ischemic stroke in mice and humans

This study examines chronic neurological changes after ischemic stroke in mice and humans, finding persistent inflammation, neuronal damage, and signs of accelerated aging in the brain.

Repeated Mild Head Injury Establishes a Senescent Cranial Bone Marrow Niche that Impairs Brain Metabolism

This study shows that repeated mild head injury leads to senescence in cranial bone marrow, impairing brain metabolism and causing systemic inflammation.