Identification of RING E3 pseudoligases in the TRIM protein family
Jane Dudley-Fraser, Diego Esposito, Katherine A. McPhie, Coltrane Morley-Williams, Tania Auchynnikava, Katrin Rittinger
The paper identifies RING E3 pseudoligases in the TRIM protein family by analyzing their structure and ubiquitin ligase activity, revealing structural divergence that impairs their function.
Nature Communications · Apr 11, 2025Peer-reviewedBiochemistry