NeuroscienceJournal of NeurophysiologyPeer-reviewed
PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model.
R. Ryley Parrish, Connie A. Mackenzie-Gray Scott, Darren A. Walsh…·Andrew J. Trevelyan
This study shows that reducing PGC-1α in PV interneurons decreases seizure-like activity in an acute epilepsy model by limiting interneuron firing intensity.
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