Sox9 links biliary maturation to branching morphogenesis
Hannah R. Hrncir, Sergei Bombin, Brianna Goodloe, Connor B. Hogan, Othmane Jadi, Adam D. Gracz
This study shows that Sox9 is essential for the development of small bile ductules during intrahepatic bile duct morphogenesis, with loss of Sox9 leading to impaired branching and BEC maturation.
bioRxiv · Jan 15, 2024 · PreprintDevelopmental Biology