Hannah R. Hrncir

The paper identifies BEC subpopulations and their spatial organization using scRNA-seq and metagenes, revealing subpopulation-specific damage responses in mouse liver.

This paper develops a 3D imaging and analysis pipeline for intrahepatic bile ducts in mouse and human tissues, revealing structural changes in health and disease.

This study shows that Sox9 is essential for the development of small bile ductules during intrahepatic bile duct morphogenesis, with loss of Sox9 leading to impaired branching and BEC maturation.