Marker-based CRISPR screens identify POU2F1 as a regulator of DLL3 and neuroendocrine identity in small cell lung cancer
Patrick J. Cunniff, Connor Fitzpatrick, Jack Bauer, Damianos S. Skopelitis, Olaf Klingbeil, Toyoki Yoshimoto, Leemor Joshua‐Tor, Christopher R. Vakoc
The paper identifies POU2F1 as a key regulator of DLL3 and neuroendocrine identity in SCLC through CRISPR screens and epigenomic analysis.
bioRxiv · Apr 10, 2026 · PreprintCancer Biology