The histone demethylase KDM5 controls developmental timing in Drosophila by promoting prothoracic gland endocycles.
Coralie Drelon, Michael F. Rogers, Helen M. Belálcazar, Julie Secombe
This study identifies KDM5 as a critical regulator of prothoracic gland function in Drosophila by promoting endoreplication and ecdysone biosynthesis.
Development · Dec 15, 2019Peer-reviewedDevelopmental Biology