Author

Corinna Brunckhorst

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Ardan Muammer SaguneriD· 1 shared Chuanyu Wei· 1 shared Cynthia A. JamesiD· 1 shared Daniel Philip JudgeiD· 1 shared Fırat DuruiD· 1 shared Huei-Sheng Vincent CheniD· 1 shared Hugh G CalkinsiD· 1 shared Joseph Edward MarineiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Ardan Muammer SagunerORCID

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1 paper

Recent·Most cited

Desmoplakin mutations in cardiac fibroblasts cause TGF?1-mediated pathological fibrogenesis in desmoplakin cardiomyopathy via beclin-1 regulation

Chuanyu Wei, Shing Fai Chan, Ardan Muammer Saguner, Corinna Brunckhorst, Fırat Duru, Joseph Edward Marine, Cynthia A. James, Hugh G Calkins, Daniel Philip Judge, Weinian Shou, Huei-Sheng Vincent Chen

This study shows that DSP mutations in cardiac fibroblasts enhance TGFβ1-induced fibrosis by disrupting beclin-1 regulation and autophagy, leading to excessive collagen accumulation and fibrotic gene activation.

Circulation Research · Aug 19, 2026Peer-reviewedCell Biology