Author

Huei-Sheng Vincent Chen

Indiana University IndianapolisORCID 0000-0002-5235-2505Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Ardan Muammer SaguneriD· 1 shared Chuanyu Wei· 1 shared Corinna Brunckhorst· 1 shared Cynthia A. JamesiD· 1 shared Daniel Philip JudgeiD· 1 shared Fırat DuruiD· 1 shared Hugh G CalkinsiD· 1 shared Joseph Edward MarineiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Ardan Muammer SagunerORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Cell BiologyCirculation ResearchPeer-reviewedAug 19, 2026

Desmoplakin mutations in cardiac fibroblasts cause TGF?1-mediated pathological fibrogenesis in desmoplakin cardiomyopathy via beclin-1 regulation

Chuanyu Wei, Shing Fai Chan, Ardan Muammer Saguner…·Huei-Sheng Vincent Chen

This study shows that DSP mutations in cardiac fibroblasts enhance TGFβ1-induced fibrosis by disrupting beclin-1 regulation and autophagy, leading to excessive collagen accumulation and fibrotic gene activation.

DOI 10.1161/circresaha.124.325512

humanbulk RNA-seq

𝕏 PostBluesky