Author

Cory Thomas Lee

Charité – Universitätsmedizin Berlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Aleksej ZelezniakiD· 1 shared Antonis RokasiD· 1 shared Benjamin Murray HeineikeiD· 1 shared Federica AgostiniiD· 1 shared Feiran LiiD· 1 shared Jacob Lucas SteenwykiD· 1 shared Jens NielseniD· 1 shared Judith G. BermaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Aleksej ZelezniakORCID

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1 paper

Recent·Most cited

The Role of Metabolism in Shaping Enzyme Structures Over 400 Million Years of Evolution

Oliver Lemke, Benjamin Murray Heineike, Sandra Viknander, Nir Cohen, Feiran Li, Jacob Lucas Steenwyk, Leonard Spranger, Federica Agostini, Cory Thomas Lee, Simran Kaur Aulakh, Judith G. Berman, Antonis Rokas, Jens Nielsen, Toni Ingolf Gossmann, Aleksej Zelezniak, Markus Ralser

This study uses AlphaFold2 to analyze how metabolism influenced enzyme structural evolution across 400 million years by examining 11,269 enzyme structures and their metabolic reactions.

Nature · Jul 9, 2025Peer-reviewedSystems Biology