Nir Cohen

The paper develops hMultiCLEM, a high-resolution screening pipeline combining EM and multiplexed human cell pools to identify proteins affecting mitochondrial cristae shape, uncovering MISHA linked to Meniere's disease.

This study identifies 34 drugs that affect antifungal efficacy in Candida albicans, with some promoting resistance when combined with fluconazole.

This study uses AlphaFold2 to analyze how metabolism influenced enzyme structural evolution across 400 million years by examining 11,269 enzyme structures and their metabolic reactions.

The paper develops ABOLISH, a method to reduce endogenous biotinylation in yeast, enabling more accurate detection of both stable and transient protein interactions using biotin ligases.

This study uses APEX proximity-proteomics to analyze the spatio-temporal proteomic changes during stress granule disassembly, identifying novel proteins and revealing SUMOylation's role in ALS pathogenesis.