Author

Cristina R. Hofman

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

David R. CoreyiD· 2 shared Jiaxin HuiD· 2 shared Victor Tse· 2 shared Rut BryliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

David R. CoreyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 8, 2025

Nuclear Argonaute:miRNA complexes recognize target sequences within chromatin and silence gene expression

Cristina R. Hofman, Jiaxin Hu, Rut Bryl…·David R. Corey

This study identifies nuclear miRNA:Argonaute complexes and their chromatin-associated RNA targets, showing miRNA-mediated gene silencing occurs in both nucleus and cytoplasm.

DOI 10.1101/2025.05.08.652285

humanChIP-seq

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BiochemistrybioRxivPreprintMay 7, 2025

Small molecule inhibition of CPSF3 impacts R-loop distribution

Cristina R. Hofman, Victor Tse, Jiaxin Hu, David R. Corey

The paper tests the effect of CPSF3 inhibitors YT-II-100 and JTE-607 on R-loop formation, finding global increases but no effect on specific R-loop positive control genes.

1 citation

experimental assay

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