Inhibiting LXRα Phosphorylation in Hematopoietic Cells Reduces Inflammation and Attenuates Atherosclerosis and Obesity
Maud Voisin, Elina Shrestha, Claire Rollet, Cyrus A. Nikain, Tatjana Josefs, Mélanie Mahé, Tessa J. Barrett, Hye Rim Chang, Rachel Ruoff, Jeffrey A. Schneider, Michela L. Garabedian, Chris Zoumadakis, Chi Yun, Bara A. Badwan, Dr. Emily J. Brown, , Michael J. Garabedian
This study shows that inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and improves atherosclerosis and obesity by altering macrophage and adipose tissue gene expression.
Communications Biology · Mar 26, 2021Peer-reviewedMolecular Biology