Elina Shrestha

This study shows that inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and improves atherosclerosis and obesity by altering macrophage and adipose tissue gene expression.

This study shows that phosphorylation of LXRα affects atherosclerosis regression by altering macrophage trafficking in diabetic mice.

This study shows that preventing LXRα phosphorylation at Ser196 reduces hepatic inflammation and fibrosis in mice on a high-fat diet, revealing a novel role for LXR phosphorylation in diet-induced transcriptome changes.