Separation of hemodynamic signals from GCaMP fluorescence measured with widefield imaging
Matthew T. Valley, M. G. Moore, Jun Zhuang, N Mesa, D Castelli, D Sullivan, Mark Reimers, Jack Waters
The paper develops a spatially-detailed regression model to separate hemodynamic signals from GCaMP fluorescence in widefield imaging of awake mice, improving accuracy near blood vessels and along the sagittal midline.
Journal of Neurophysiology · Nov 20, 2019Peer-reviewedNeuroscience