M. G. Moore

Gene Expression Changes in Cultured Reactive Rat Astrocyte Models and Comparison to Device-Associated Effects in the Brain

The paper compares gene expression in reactive astrocyte culture models to spatial transcriptomics data from implanted devices in rat brains, identifying shared genes and biomarkers of the foreign body response.

Separation of hemodynamic signals from GCaMP fluorescence measured with widefield imaging

The paper develops a spatially-detailed regression model to separate hemodynamic signals from GCaMP fluorescence in widefield imaging of awake mice, improving accuracy near blood vessels and along the sagittal midline.