Matthew T. Valley

Learning from unexpected events in the neocortical microcircuit

The paper shows that cortical pyramidal neurons exhibit distinct unexpected event signals in somata and distal apical dendrites that change over days, suggesting a role in hierarchical computation.

Differential encoding of temporal context and expectation under representational drift across hierarchically connected areas

The paper shows that visual areas differentially encode temporal context and expectation in natural scenes, with representational drift observed in lower areas but not higher ones.

Separation of hemodynamic signals from GCaMP fluorescence measured with widefield imaging

The paper develops a spatially-detailed regression model to separate hemodynamic signals from GCaMP fluorescence in widefield imaging of awake mice, improving accuracy near blood vessels and along the sagittal midline.

A suite of transgenic driver and reporter mouse lines with enhanced brain cell type targeting and functionality

The paper introduces a new set of transgenic mouse lines for precise targeting and manipulation of brain cell types, enhancing genetic tools for neuroscience research.

Aberrant Cortical Activity In Multiple GCaMP6-Expressing Transgenic Mouse Lines

The paper reports aberrant cortical activity and fluorescence events in some GCaMP6-expressing transgenic mice, suggesting potential artifacts in neuronal recordings.