Author

D. A. Goulding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

A. V. Ion· 1 shared C. Ludden· 1 shared G. Dougan· 1 shared H.-C. Cheng· 1 shared J. Bartholdson Scott· 1 shared J. C. D'Aeth· 1 shared M. J. Kwun· 1 shared M. Maes· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. V. Ion

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-coding RNA

M. J. Kwun, A. V. Ion, H.-C. Cheng, J. C. D'Aeth, S. Dougan, M. R. Oggioni, D. A. Goulding, S. D. Bentley, N. J. Croucher

The paper identifies prophage-driven modification of a non-coding RNA that inhibits transformation in pneumococci, explaining the persistence of serotype 3 despite vaccination.

bioRxiv · Sep 21, 2022Microbiology

A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131

M. Maes, Z. A. Dyson, S. E. Smith, D. A. Goulding, C. Ludden, S. Baker, P. Kellam, S. T. Reece, G. Dougan, J. Bartholdson Scott

This study uses high-content imaging to screen a monoclonal antibody against E. coli ST131 isolates, identifying four binding phenotypes and linking them to genetic variations affecting O-antigen structure.

bioRxiv · May 22, 2020Microbiology