Expression attenuation as a mechanism of robustness to gene duplication in protein complexes
D. Ascencio, G. Diss, I. Gagnon-Arsenault, A. K. Dube, A. DeLuna, C. R. Landry
The paper investigates the fitness effects of gene duplication in budding yeast, finding that most protein complex subunits have minimal fitness impact, while large complexes are protected by reduced protein abundance.
bioRxiv · Jul 9, 2020 · PreprintEvolutionary Biology