The AAA-ATPase Atad1 and its partners promote degradation of desmin intermediate filaments in muscle
This study identifies ATAD1 and its partners PLAA and UBXN4 as facilitators of desmin intermediate filament degradation in muscle, revealing their role in promoting ubiquitinated desmin release and calpain-1 cleavage.
bioRxiv · Jan 24, 2022Cell Biology