A selective GSK3β inhibitor, tideglusib, decreases intermittent access and binge ethanol self-administration in C57BL/6J mice
S. Gottlieb, A. van der Vaart, A. Hassan, D. Bledsoe, A. Morgan, B. O'Rourke, W. D. Rogers, J. T. Wolstenholme, M. F. Miles
This study shows that tideglusib, a GSK3β inhibitor, reduces ethanol consumption in mice without affecting water intake or anxiety-like behavior.
bioRxiv · May 13, 2024Pharmacology & Toxicology