Regulation of FXR1 by alternative splicing is required for muscle development and controls liquid-like condensates in muscle cells
J. A. Smith, E. G. Curry, R. E. Blue, C. Roden, S. E. R. Dundon, A. Rodriguez-Vargas, D. C. Jordan, X. Chen, S. M. Lyons, J. Crutchley, P. Anderson, M. E. Horb, A. S. Gladfelter, J. Giudice
This study shows that alternative splicing of FXR1 regulates its function in muscle development by controlling RNA-dependent condensates and disease-related mis-splicing.
bioRxiv · Oct 24, 2019Cell Biology