Author

J. Giudice

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

Y.-H. Tsai· 2 shared A. Chatterjee· 1 shared A. E. D. Van Swearingen· 1 shared A. L. Amelio· 1 shared A. M. Musicant· 1 shared A. Porrello· 1 shared A. Rodriguez-Vargas· 1 shared A. S. Gladfelter· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCancer Biology

Y.-H. Tsai

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Author profile →

4 papers

Recent·Most cited

Requirements for efficient endosomal escape by designed mini-proteins

J. Giudice, D. D. Brauer, M. Zoltek, A. Vazquez, M. J. S. Kelly, A. Schepartz

This paper identifies the requirements for efficient endosomal escape by ZF5.3, a mini-protein, showing pH-induced unfolding and lipid-BMP interaction are critical for its function.

bioRxiv · Apr 5, 2024 · PreprintBiochemistry

Snord67 promotes lymph node metastasis and regulates U6-mediated alternative splicing in breast cancer

Y. L. Chao, Y. Zhu, H. J. Wiedner, Y.-H. Tsai, L. Wilkinson, A. Porrello, A. E. D. Van Swearingen, L. A. Carey, J. Giudice, C. L. Holley, C. V. Pecot

This study identifies Snord67 as a regulator of lymph node metastasis in breast cancer by modulating U6-mediated alternative splicing.

bioRxiv · Aug 28, 2020 · PreprintCancer Biology

CRTC1-MAML2 Establishes a PGC1α-IGF1 Circuit that Confers Vulnerability to PPARγ Inhibition

A. M. Musicant, K. Parag-Sharma, W. Gong, M. Sengupta, A. Chatterjee, E. C. Henry, Y.-H. Tsai, M. Hayward, S. Sheth, R. Betancourt, T. Hackman, R. J. Padilla, J. S. Parker, J. Giudice, C. A. Flaveny, , A. L. Amelio

This study identifies a CRTC1-MAML2-driven transcriptional circuit involving PGC-14 and IGF-1 that makes mucoepidermoid carcinoma cells vulnerable to PPARγ inhibition.

bioRxiv · Jun 3, 2020 · PreprintCancer Biology

Regulation of FXR1 by alternative splicing is required for muscle development and controls liquid-like condensates in muscle cells

J. A. Smith, E. G. Curry, R. E. Blue, C. Roden, S. E. R. Dundon, A. Rodriguez-Vargas, D. C. Jordan, X. Chen, S. M. Lyons, J. Crutchley, P. Anderson, M. E. Horb, A. S. Gladfelter, J. Giudice

This study shows that alternative splicing of FXR1 regulates its function in muscle development by controlling RNA-dependent condensates and disease-related mis-splicing.

bioRxiv · Oct 24, 2019Cell Biology