Author

D. C. Wan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. Henn· 3 shared K. Chen· 3 shared M. Januszyk· 3 shared M. T. Longaker· 3 shared C. A. Bonham· 2 shared D. Sivaraj· 2 shared G. C. Gurtner· 2 shared M. Griffin· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCell Biology

D. Henn

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition

M. Griffin, H. Talbott, N. Guardino, J. Guo, A. Spielman, K. Chen, S. Mascharak, J. Parker, D. Henn, N. Liang, M. King, A. Cotterell, K. Bauer-Rowe, D. Abbas, N. M. D. Deleon, , M. T. Longaker

This study shows that inhibiting Piezo1 or Piezo2 prevents adipocyte-to-fibroblast transition, reducing scarring in wounds and suggesting a therapeutic target for fibrosis.

bioRxiv · Apr 3, 2023 · PreprintCell Biology

Xenogeneic Skin Transplantation Promotes Angiogenesis and Tissue Regeneration Through Vitamin D-Activated Trem2+ Macrophages

D. Henn, K. Chen, T. Fehlmann, D. Sivaraj, Z. Maan, C. A. Bonham, J. A. Barrera, C. J. Mays, A. H. Greco, S. E. Moortgat Illouz, J. Q. Lin, D. Foster, J. Padmanabhan, A. Momeni, D. Nguyen, , G. C. Gurtner

The paper shows that vitamin D-activated Trem2+ macrophages promote angiogenesis and reduce fibrosis, offering a new strategy for advanced cell therapies in complex wounds.

bioRxiv · Feb 26, 2021Immunology

Divergent molecular signatures of regeneration and fibrosis during wound repair

S. Mascharak, H. E. desJardins-Park, M. Januszyk, K. Chen, M. F. Davitt, J. Demeter, D. Henn, M. Griffin, C. A. Bonham, D. S. Foster, N. A. Mooney, R. Cheng, P. K. Jackson, D. C. Wan, G. C. Gurtner, M. T. Longaker

This study identifies divergent molecular signatures of regeneration and fibrosis during wound repair using multimodal analysis.

bioRxiv · Dec 17, 2020 · PreprintCell Biology