Author

N. Guardino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. B. Hwang· 1 shared A. Chareunsouk· 1 shared A. Cotterell· 1 shared A. Krez· 1 shared A. S. Brack· 1 shared A. Spielman· 1 shared B. Alman· 1 shared C. A. Watson· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. B. Hwang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition

M. Griffin, H. Talbott, N. Guardino, J. Guo, A. Spielman, K. Chen, S. Mascharak, J. Parker, D. Henn, N. Liang, M. King, A. Cotterell, K. Bauer-Rowe, D. Abbas, N. M. D. Deleon, , M. T. Longaker

This study shows that inhibiting Piezo1 or Piezo2 prevents adipocyte-to-fibroblast transition, reducing scarring in wounds and suggesting a therapeutic target for fibrosis.

bioRxiv · Apr 3, 2023 · PreprintCell Biology

LCP1 Regulates Cell Motility in Chondrosarcoma and Correlates with Metastatic Potential and Poor Patient Outcomes

C. A. Watson, J. T. Martin, M. Nakagawa, N. Guardino, T. Zou, E. Peairs, A. Krez, P. Nadesan, Z. Huang, J. Ou, J. Somarelli, B. Alman, J. D. Visgauss

This study identifies LCP1 as a driver of metastasis and poor prognosis in chondrosarcoma through gene expression analysis and in vitro experiments.

bioRxiv · Jan 31, 2023 · PreprintCancer Biology

PDH Mediated Mitochondrial Respiration Controls the Speed of Muscle Stem Cell Activation in Muscle Repair and Aging

M. H. Raval, P.-C. Cheng, N. Guardino, S. Ahsan, H. Zhou, R. L. Tiwari, L. Wang, A. Chareunsouk, M. Ederer, A. B. Hwang, M. Ellenberger, R. Pepin, D. Pormislow, K. Shen, A. S. Brack, J. T. Rodgers

This study shows that mitochondrial respiration via PDH controls the speed of muscle stem cell activation, which declines with age, and that restoring PDH activity can improve muscle regeneration in aged mice.

bioRxiv · Feb 14, 2020 · PreprintCell Biology