Author

D. Calderwood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Li· 1 shared B. K. Rajendran· 1 shared B. Turk· 1 shared D. Wu· 1 shared H. Zhou· 1 shared J. Ren· 1 shared W. Li· 1 shared W. Tang· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Li

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1 paper

Recent·Most cited

The Cul5 E3 Ligase Complex Is a Key Negative Feedback Regulator of TCR/IL2 Signaling and Anti-Tumor Activity in CD8+ T Cells

X. Liao, W. Li, A. Li, B. K. Rajendran, J. Ren, H. Zhou, D. Calderwood, B. Turk, W. Tang, Y. Liu, D. Wu

This study identifies Cul5 as a negative feedback regulator of CD8+ T cell signaling and anti-tumor activity, showing its knockout enhances tumor control through proteomic and signaling changes.

bioRxiv · Nov 16, 2022 · PreprintImmunology