Author

B. K. Rajendran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. Wu· 3 shared H. Zhou· 3 shared W. Tang· 3 shared W. Li· 2 shared Y. Liu· 2 shared Y. Luan· 2 shared A. Dardik· 1 shared A. Li· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

D. Wu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease

S. P. Srivastava, H. Zhou, R. Shenoi, M. Morris, L. Goedeke, B. K. Rajendran, O. Setia, B. Aryal, K. Kanasaki, D. Koya, A. Dardik, T. Bell, C. Fernandez-Hernando, G. Shulman, J. E. Goodwin

This study identifies Angptl4 as a fibrogenic molecule in diabetic kidney disease and shows that targeting its expression in kidneys reduces fibrosis and proteinuria.

bioRxiv · Nov 8, 2023Cell Biology

Loss of WNT5 Proteins Reprograms Neutrophils in the Spleen to Provide Protection for DSS-Induced Colitis

Y. Luan, J. Hu, Q. Wang, W. Li, X. Wang, R. Qu, B. K. Rajendran, H. Zhou, P. Liu, Y. Shi, Y. Liu, J. Lu, W. Tang, D. Wu

This study shows that loss of WNT5A and WNT5B in mice protects against DSS-induced colitis by reprogramming spleen neutrophils to suppress inflammation.

bioRxiv · Jan 28, 2023 · PreprintImmunology

Lack of Fzd6 in Ciliated Cells Suppresses Ferroptotic Pulmonary Alveolar Cell Death Induced by LPS and Coronavirus

Q. Yuan, Y. Luan, B. K. Rajendran, S. Compton, W. Tang, D. Wu

This study shows that Fzd6 deficiency in ciliated cells reduces pulmonary inflammation-induced cell death by increasing Akr1b8 expression and protecting against ferroptosis.

bioRxiv · Jan 23, 2023 · PreprintPathology

The Cul5 E3 Ligase Complex Is a Key Negative Feedback Regulator of TCR/IL2 Signaling and Anti-Tumor Activity in CD8+ T Cells

X. Liao, W. Li, A. Li, B. K. Rajendran, J. Ren, H. Zhou, D. Calderwood, B. Turk, W. Tang, Y. Liu, D. Wu

This study identifies Cul5 as a negative feedback regulator of CD8+ T cell signaling and anti-tumor activity, showing its knockout enhances tumor control through proteomic and signaling changes.

bioRxiv · Nov 16, 2022 · PreprintImmunology