Author

D. Despotopoulou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Kostarelos· 2 shared M. Stylianou· 2 shared N. Lozano· 2 shared T. Kisby· 2 shared A. S. MacDonald· 1 shared A. Thawley· 1 shared H. Parker· 1 shared K. Arashvand· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersBioengineering

K. Kostarelos

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2 papers

Recent·Most cited

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

M. Stylianou, T. Kisby, D. Despotopoulou, H. Parker, A. Thawley, K. Arashvand, N. Lozano, A. S. MacDonald, K. Kostarelos

This paper demonstrates that graphene oxide nanosheets loaded with a TLR7/8 agonist can reprogram tumor-associated macrophages in GBM to a pro-inflammatory state, reducing tumor burden.

bioRxiv · Sep 18, 2023Bioengineering

Engineering of a graphene oxide-based two-dimensional platform for immune activation and modulation

D. Despotopoulou, M. Stylianou, L. M. Arellano, T. Kisby, N. Lozano, K. Kostarelos

This study designs graphene oxide-based nanosheets to form stable complexes with the TLR7/8 agonist R848, preserving its biological activity and demonstrating effective macrophage activation.

bioRxiv · Aug 22, 2023 · PreprintBioengineering