Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM
K. Saotome, D. Dudgeon, K. Colotti, M. J. Moore, J. Jones, Y. Zhou, A. Rafique, G. D. Yancopoulos, A. J. Murphy, J. C. Lin, W. C. Olson, M. C. Franklin
The paper reports cryoEM structures of TCR-CD3 complexes and pMHC ligands, revealing structural insights into TCR recognition of cancer antigens.
bioRxiv · Aug 18, 2022Biochemistry