Spontaneous aggressive ERα+ mammary tumor model is driven by Kras activation
K. M. Campbell, K. A. O'Leary, D. E. Rugowski, W. A. Mulligan, E. K. Barnell, Z. L. Skidmore, K. Krysiak, M. Griffith, L. A. Schuler, O. L. Griffith
This study identifies Kras activation as a driver of spontaneous ERα+ mammary tumors in a murine model, validated through genomic and transcriptomic analyses.
bioRxiv · Oct 16, 2018Cancer Biology