Author

D. E. Schones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Zirbes· 2 shared M. A. LaBarge· 2 shared M. E. Todhunter· 2 shared M. Miyano· 2 shared M. R. Stampfer· 2 shared P. Senapati· 2 shared R. W. Sayaman· 2 shared S. L. Neuhausen· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Zirbes

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2 papers

Recent·Most cited

Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

R. W. Sayaman, M. Miyano, P. Senapati, A. Zirbes, S. Shalabi, M. E. Todhunter, V. Seewaldt, S. L. Neuhausen, M. R. Stampfer, D. E. Schones, M. A. LaBarge

The paper identifies age-related gene expression changes in luminal epithelial cells that contribute to breast cancer susceptibility and develops a classifier to distinguish normal from cancer tissue.

bioRxiv · Sep 22, 2022Cancer Biology

Epigenetic changes with age primes mammary luminal epithelia for cancer initiation

R. W. Sayaman, M. Miyano, P. Senapati, S. Shalabi, A. Zirbes, M. E. Todhunter, V. Seewaldt, S. L. Neuhausen, M. R. Stampfer, D. E. Schones, M. A. LaBarge

The paper shows how age-related epigenetic and gene expression changes in mammary luminal epithelia prime cells for cancer initiation, with implications for subtype-specific cancer susceptibility.

bioRxiv · Feb 12, 2021 · PreprintCancer Biology