Author

S. L. Neuhausen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Zirbes· 2 shared C. Patrick· 2 shared D. E. Schones· 2 shared J. N. Weitzel· 2 shared M. A. LaBarge· 2 shared M. E. Todhunter· 2 shared M. Miyano· 2 shared M. R. Stampfer· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

A. Zirbes

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

R. W. Sayaman, M. Miyano, P. Senapati, A. Zirbes, S. Shalabi, M. E. Todhunter, V. Seewaldt, S. L. Neuhausen, M. R. Stampfer, D. E. Schones, M. A. LaBarge

The paper identifies age-related gene expression changes in luminal epithelial cells that contribute to breast cancer susceptibility and develops a classifier to distinguish normal from cancer tissue.

bioRxiv · Sep 22, 2022Cancer Biology

Profile of the somatic mutational landscape in breast tumors from Hispanic/Latina women

Y. C. Ding, H. Song, A. Adamson, D. Schmolze, D. Hu, S. Huntsman, L. Steele, C. Patrick, N. Hernandez, C. D. Adams, L. Fejerman, K. L. Gardner, A. M. Napoles, E. J. Perez-Stable, J. N. Weitzel, , E. Ziv

This study analyzes the somatic mutational landscape of breast tumors in Hispanic/Latina women using whole-exome and RNA-seq, identifying common mutations and novel mutation signatures.

bioRxiv · Aug 1, 2022 · PreprintCancer Biology

Variable Number Tandem Repeats (VNTRs) as modifiers of breast cancer risk in carriers of BRCA1 185delAG

Y. C. Ding, A. W. Adamson, M. Bakhtiari, C. Patrick, J. Park, Y. Laitman, J. N. Weitzel, V. Bafna, E. Friedman, S. L. Neuhausen

This study identifies VNTRs as modifiers of breast cancer risk in BRCA1 185delAG carriers, finding several VNTRs significantly associated with earlier age of onset compared to SNPs.

bioRxiv · Jun 1, 2022Cancer Biology

Epigenetic changes with age primes mammary luminal epithelia for cancer initiation

R. W. Sayaman, M. Miyano, P. Senapati, S. Shalabi, A. Zirbes, M. E. Todhunter, V. Seewaldt, S. L. Neuhausen, M. R. Stampfer, D. E. Schones, M. A. LaBarge

The paper shows how age-related epigenetic and gene expression changes in mammary luminal epithelia prime cells for cancer initiation, with implications for subtype-specific cancer susceptibility.

bioRxiv · Feb 12, 2021 · PreprintCancer Biology