Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition
N. M. Karabacak, Y. Zheng, T. D. Dubash, R. Burr, D. S. Micalizzi, B. S. Wittner, D. F. Wiley, V. Comaills, E. Emmons, K. Niederhoffer, U. Ho, L. Nieman, W. Haas, S. L. Stott, D. T. Ting, , S. Maheswaran
The paper uses single cell proteomics to identify kinase activity differences in tumor compartments, showing how they affect sensitivity to mTOR-PI3K inhibition.
bioRxiv · Jan 6, 2021 · PreprintCancer Biology