LKB1 is the gatekeeper of carotid body chemo-sensing and the hypoxic ventilatory response
S. MacMillan, A. P. Holmes, M. L. Dallas, A. D. Mahmoud, M. J. Shipston, D. G. Hardie, P. Kumar, A. M. Evans
This study identifies LKB1 as essential for carotid body chemosensing and the hypoxic ventilatory response, showing divergence in LKB1 and AMPK dependency between the carotid body and the HVR.
bioRxiv · May 24, 2022 · PreprintPhysiology