Author

D. G. Patterson

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. K. Kania· 1 shared C. D. Scharer· 1 shared J. M. Boss· 1 shared J. R. Rose· 1 shared M. J. Price· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. K. Kania

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1 paper

Recent·Most cited

An IRF4-MYC-mTORC1 integrated pathway controls cell growth and the proliferative capacity of activated B cells during B cell differentiation in vivo

D. G. Patterson, A. K. Kania, M. J. Price, J. R. Rose, C. D. Scharer, J. M. Boss

This study identifies an IRF4-MYC-mTORC1 pathway critical for B cell proliferation and growth during differentiation, showing IRF4 regulates MYC and mTORC1 to drive metabolic reprogramming and cell cycle progression.

bioRxiv · Jun 20, 2021Immunology