Cryo-EM Structure of HRSL Domain Reveals Activating Crossed Helices at the Core of GCN2
K. Solorio - Kirpichyan, D. Golovenko, A. Korostelev, N. Yan, A. Korennykh
The paper reports a cryo-EM structure of the HRSL domain from GCN2, revealing its role in activating the kinase and regulating the ISR pathway.
bioRxiv · Apr 24, 2024Biochemistry