An affinity-matured DLL4 ligand for broad-spectrum activation and inhibition of Notch signaling
D. Gonzalez-Perez, S. Das, E. Medina, D. Antfolk, E. D. Egan, S. C. Blacklow, P. C. Rodriguez, V. C. Luca
This study develops DeltaMAX, an affinity-matured DLL4 ligand that broadly activates or inhibits Notch signaling in human and murine systems.
bioRxiv · Mar 7, 2022 · PreprintBioengineering