D. Antfolk

Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping.

This study shows that Notch1's N1ICD forms transcriptional condensates via phase separation coupled percolation, enhancing target gene expression and enhancer looping.

An affinity-matured DLL4 ligand for broad-spectrum activation and inhibition of Notch signaling

This study develops DeltaMAX, an affinity-matured DLL4 ligand that broadly activates or inhibits Notch signaling in human and murine systems.