A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus
M. Inthawong, N. Pinthong, A. Thaiprakhong, T. Wangrangsimakul, P. Sunyakumthorn, J. Hill, P. Sonthayanon, D. H. Paris, S. Dunachie, B. Kronsteiner
This study optimizes a whole blood intracellular cytokine assay to assess polyfunctional CD4+ T cell responses in acute scrub typhus, demonstrating its utility in field settings with limited resources.
bioRxiv · Oct 28, 2022Immunology