Author

D. I. Freedberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:fungi (other)· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. A. Hargett· 2 shared M. P. Wear· 2 shared A. A. Casadevall· 1 shared A. Casadevall· 1 shared C. Crawford· 1 shared C. J. Crawford· 1 shared H. F. Azurmendi· 1 shared J. E. Kelly· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

A. A. Hargett

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2 papers

Recent·Most cited

The structure of a C. neoformans polysaccharide motif recognized by protective antibodies: a combined NMR and MD study

A. A. Hargett, H. F. Azurmendi, C. J. Crawford, M. P. Wear, S. Oscarson, A. A. Casadevall, D. I. Freedberg

This study uses NMR and MD simulations to determine the structure of a synthetic C. neoformans polysaccharide, revealing its extended conformation and structural features recognized by protective antibodies.

bioRxiv · Sep 6, 2023 · PreprintBiochemistry

Lyophilization induces alterations in cryptococcal exopolysaccharide resulting in reduced antibody binding

M. P. Wear, A. A. Hargett, J. E. Kelly, S. A. McConnell, C. Crawford, D. I. Freedberg, R. E. E. Stark, A. Casadevall

This study shows that lyophilization alters the structure of Cryptococcus neoformans exopolysaccharide, reducing antibody binding.

bioRxiv · Mar 4, 2022 · PreprintMicrobiology