Cell BiologybioRxiv
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
DOI 10.1038/s44318-024-00328-6
Author
D. J. van den Boomen
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2023 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 19 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Cell BiologybioRxiv
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export
D. J. van den Boomen, A. Sienkiewicz, I. Berlin…·P. J. Lehner
The paper identifies C18orf8 as a core component of the Mon1-Ccz1 GEF for Rab7, showing its role in Rab7 activation, endosomal LDL trafficking, and NPC1-dependent lysosomal cholesterol export.
DOI 10.1038/s41467-020-19032-0 - Cell BiologybioRxiv
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
N. Volkmar, S. A. Menzies, D. J. van den Boomen…·P. J. Lehner
This study identifies RNF145 as a sterol-responsive E3 ubiquitin ligase that, along with gp78 and Hrd1, mediates HMGCR degradation in response to sterol levels.
DOI 10.7554/elife.40009