Author

N. Volkmar

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. S. Dickson· 1 shared D. J. van den Boomen· 1 shared J. A. Nathan· 1 shared P. J. Lehner· 1 shared R. T. Timms· 1 shared S. A. Menzies· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

A. S. Dickson

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1 paper

Recent·Most cited

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

N. Volkmar, S. A. Menzies, D. J. van den Boomen, R. T. Timms, A. S. Dickson, J. A. Nathan, P. J. Lehner

This study identifies RNF145 as a sterol-responsive E3 ubiquitin ligase that, along with gp78 and Hrd1, mediates HMGCR degradation in response to sterol levels.

bioRxiv · Aug 14, 2018Cell Biology