D. J. Yanofsky

Structure of mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203)

This study determines the structure of the mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug telacebec, revealing its mechanism of inhibiting menaquinol oxidation.

The respiratory supercomplex from C. glutamicum

This paper determines the structure of the CIII2CIV2 supercomplex from C. glutamicum using cryo-EM, revealing its architecture and proton transport pathway.