Author

D. K. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:Hi-C· 1

Frequent Co-Authors

A. C. Lima· 1 shared A. M. Stendahl· 1 shared B. Becerra Larios· 1 shared B. Ndjamen· 1 shared C. E. Layman· 1 shared D. F. Conrad· 1 shared E. E. Eichler· 1 shared G. P. Munson· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

A. C. Lima

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TAD Evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function

M. Okhovat, J. VanCampen, A. C. Lima, K. Nevonen, C. E. Layman, S. Ward, J. Herrera, A. M. Stendahl, R. Yang, L. Harshman, W. Li, R. R. Sheng, Y. Mao, L. Fedorov, B. Ndjamen, , L. Carbone

The paper analyzes TAD boundaries across species to show evolutionary conservation and functional significance, finding ultraconserved boundaries have stronger insulation and CTCF binding.

bioRxiv · Mar 7, 2023Evolutionary Biology

The AraC/XylS protein MxiE and its co-regulator IpgC control a negative feedback loop in the transcriptional cascade that regulates type III secretion in Shigella flexneri

J. A. McKenna, M. M. Karney, D. K. Chan, N. Weatherspoon-Griffin, B. Becerra Larios, M. C. Pilonieta, G. P. Munson, H. J. Wing

This paper identifies a negative feedback loop involving MxiE and IpgC that down-regulates the virB promoter in Shigella flexneri, counteracting VirF activation.

bioRxiv · Apr 20, 2022Microbiology