Drug-dependent morphological transitions in spherical and worm-like polymeric micelles define stability and pharmacological performance of micellar drugs
C. Lim, J. D. Ramsey, D. K. Hwang, S. C. M. Teixeira, C.-D. Poon, J. D. Strauss, M. Sokolsky, A. V. Kabanov
This study evaluates how the morphology of polymeric micelles affects their pharmacological performance, finding that spherical micelles are more effective for drug delivery when drugs are loosely associated.
bioRxiv · Jun 10, 2021Pharmacology & Toxicology